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Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 231-241 doi: 10.1007/s11684-013-0253-7

Abstract: PcG proteins assemble into polycomb repressive complex 1 (PRC1) and polycomb repressive complex 2 (PRC2Last but not least, we will consider the therapeutic potential of targeting enhancer of zeste homolog2 (EZH2) as a possible treatment for HCC.

Keywords： liver cancer epigenetics histone modifications polycomb group proteins enhancer of zeste homolog 2 (EZH2

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Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium

Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li

Frontiers of Medicine 2016, Volume 10, Issue 3, Pages 330-335 doi: 10.1007/s11684-016-0459-6

Abstract:

The enhancer of zeste 2 polycomb repressive complex 2 subunit (Ezh2) is a histone-lysine N-methyltransferaseEzh2 has also been reported to play crucial roles in stem cell proliferation and differentiation.At E12.5, Ezh2 was expressed in the nuclei of the cochlear prosensory epithelium.Ezh2 continued to be expressed in the cochlear epithelium of adult mice.detailed role of Ezh2 during cochlear development.

Keywords： polycomb repressive complex Ezh2 expression inner ear cochlea development

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Disabled homolog 2 is required for migration and invasion of prostate cancer cells

Yinyin Xie,Yuanliang Zhang,Lu Jiang,Mengmeng Zhang,Zhiwei Chen,Dan Liu,Qiuhua Huang

Frontiers of Medicine 2015, Volume 9, Issue 3, Pages 312-321 doi: 10.1007/s11684-015-0401-3

Abstract:

Disabled homolog 2 (DAB2) is frequently deleted or epigenetically silenced in many human cancerTherefore, DAB2 has always been regarded as a tumor suppressor gene.However, the role of DAB2 in tumor progression and metastasis remains unclear.the biological functions of DAB2 in PCa progression and metastasis.Therefore, DAB2 may play an important role in PCa progression and metastasis.

Keywords： DAB2 prostate cancer migration invasion acetylation

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Influence of short chain ceramides and lipophilic penetration enhancers on the nano-structure of stratum corneum model membranes studied using neutron diffraction

Annett SCHROETER, Tanja ENGELBRECHT, Reinhard H. H. NEUBERT

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1, Pages 29-36 doi: 10.1007/s11705-013-1302-0

Abstract: of the short chain ceramides (CER)[NP] and [AP] as well as the impact of the lipophilic penetration enhancerThe influence of the enhancer molecules were studied using specifically deuterated OA and IPM and neutronThe penetration enhancer OA has not influenced the repeat distance of the model membrane based on CERthe same effect but two phases (assigned as phase A and B) appeared, when IPM was used as penetration enhancer

Keywords： nano-structure of the stratum corneum ceramide penetration enhancer model membrane neutron diffraction ²H NMR spectroscopy

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Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1, Pages 80-84 doi: 10.1007/s11705-008-0017-0

Abstract: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl thioester(III), an importantintermediate of the fourth generation cephalosporins, was efficiently synthesized by reacting 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid (I) with 2,2′-dibenzothiazole disulfide (II) in

Keywords： 5-Amino-1 2 4-thiadiazol-3-yl 1 2-dichloroethane important intermediate 2-benzothiazolyl thioester temperature

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Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 2, Pages 142-146 doi: 10.1007/s11705-009-0233-2

Abstract: TiO-AlOmixed oxides with different compositions ranging from 40wt-% to 95wt-% of TiO were prepared by sol-gel method and impregnated with different amounts of VO. Supports and catalysts were characterized by X-ray diffraction (XRD), physisorption, temperature preprogrammed reduction (H-TPR), and ammonia temperature programmed desorption (NH-TPD). TiO content in the support had obvious effect on the crystal structure, texture characteristic, acid property, and catalytic activity in dehydrogenation of ethylbenzene (EB) with carbon dioxide. The highest catalytic activity was acquired when the TiO content was 50 wt-%.

Keywords： desorption different TiO-AlOmixed physisorption ethylbenzene

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Al₂O₃ and CeO₂-promoted MgO sorbents for CO₂ capture at moderate

Huimei Yu, Xiaoxing Wang, Zhu Shu, Mamoru Fujii, Chunshan Song

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 1, Pages 83-93 doi: 10.1007/s11705-017-1691-6

Abstract: A series of Al O and CeO modified MgO sorbents was prepared and studied for CO sorption at moderate temperatures. The CO sorption capacity of MgO was enhanced with the addition of either Al O or CeO . Over Al O -MgO sorbents, the best capacity of 24.6 mg-CO /g-sorbent was attained at 100 °C, which was 61% higher than that of MgO (15.3 mg-CO /g-sorbent). The highest capacity of 35.3 mg-CO /g-sorbent was obtained over the CeO -MgO sorbents at the optimal temperature of 200 °C. Combining with the characterization results, we conclude that the promotion effect on CO sorption with the addition of Al O and CeO can be attributed to the increased surface area with reduced MgO crystallite size. Moreover, the addition of CeO increased the basicity of MgO phase, resulting in more increase in the CO capacity than Al O promoter. Both the Al O -MgO and CeO -MgO sorbents exhibited better cyclic stability than MgO over the course of fifteen CO sorption-desorption cycles. Compared to Al O , CeO is more effective for promoting the CO capacity of MgO. To enhance the CO capacity of MgO sorbent, increasing the basicity is more effective than the increase in the surface area.

Keywords： CO₂ capture MgO sorbents Al₂O₃ CeO₂ flue gas

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A Storage-Driven CO₂ EOR for a Net-Zero Emission Target Article

Yueliang Liu, Zhenhua Rui

Engineering 2022, Volume 18, Issue 11, Pages 79-87 doi: 10.1016/j.eng.2022.02.010

Abstract: >2 emissions by storing CO₂ in oil reservoirs.CO₂ EOR—whose main target is to realize net-zero or even negative CO₂ emissionsStorage-driven CO₂ EOR is superior to conventional CO₂ EOR in improving sweepingthan conventional CO₂ EOR.Moreover, the amount of sequestrated CO2 in storage-driven CO₂ EOR exceeds the amount

Keywords： CO₂ EOR Net CO₂ emissions Dimethyl ether Storage-driven CO₂ EOR CO₂ sequestration

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The stabilization effect of Al₂O₃ on unconventional Pb/SiO₂ catalyst

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10, Pages 1423-1429 doi: 10.1007/s11705-023-2315-y

Abstract: To enhance the stability, the traditional carrier Al₂O₃ with a small amount, wasintroduced into Pb/SiO₂ catalyst in this study.It has been proved that Al₂O₃ can inhibit the reduction of PbO, and weaken theAs a result, 3Al15Pb/SiO₂ catalyst exhibits a much higher stability up to more than 150 h.addition, a simple schematic diagram of the change of surface species on the catalyst surface after Al_2<

Keywords： Pb/SiO₂ Al₂O₃ propane dehydrogenation propene stability

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Biodegradation of 2-methylisoborneol by bacteria enriched from biological activated carbon

Rongfang YUAN, Beihai ZHOU, Chunhong SHI, Liying YU, Chunlei ZHANG, Junnong GU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5, Pages 701-710 doi: 10.1007/s11783-011-0367-6

Abstract: One of the most common taste and odour compounds (TOCs) in drinking water is 2-methylisoborneol (2-MIBFour bacterial strains for degrading 2-MIB were isolated from the surface of a biological activated carbonThe removal efficiencies of 2-MIB with initial concentrations of 515 ng·L were 98.4%, 96.3%, 95.0%,The kinetic model showed that biodegradation of 2-MIB at an initial dose of 4.2 mg·L was a pseudo-first-orderThese degraders decomposed 2-MIB to form 2-methylenebornane and 2-methyl-2-bornane as the products.

Keywords： 2-methylisoborneol (2-MIB) biodegradation 2-methylenebornane 2-methyl-2-bornane pseudo-first-order reaction

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Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4, Pages 672-683 doi: 10.1007/s11705-019-1856-6

Abstract: The conventional emulsion technique was selected for the microcapsule formulation by using 2-amino-2-

Keywords： carbon capture microencapsulated sorbents emulsion technique low temperature adsorption and absorption

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Cu-doped Bi/Bi₂WO₆ catalysts for efficient N₂ fixation by photocatalysis

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10, Pages 1412-1422 doi: 10.1007/s11705-023-2312-1

Abstract: In this paper, Cu-doped Bi₂WO₆ was synthesized via a solvothermal method and appliedit in photocatalytic N₂ immobilization.metallic Bi in the photocatalyst, indicating that the synthesized photocatalyst is actually Bi/Cu-Bi_{22 and most likely substituted the position of Bi³⁺.Cu did not affect the metallic Bi content, but mainly influenced the energy band structure of Bi_2<}

Keywords： Bi₂WO₆ Cu doping work function photocatalytic N₂ fixation charge

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Fenton oxidation of 2,4- and 2,6-dinitrotoluene and acetone inhibition

HE Yiliang, ZHAO Bin, HUGHES Joseph B., HAN Sung Soo

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 3, Pages 326-332 doi: 10.1007/s11783-008-0038-4

Abstract: The performances and kinetic parameters of Fenton oxidation of 2,4- and 2,6-dinitrotoluene (DNT) in water-acetone- and 2,6-DNT.- and 2,6-DNT completely, mainly due to the competition of hydroxyl radicals.Fenton oxidation of 2,4- and 2,6-DNT fit well with the first-order kinetics and the presence of acetone-DNT primary degradation was proposed: 2,4-DNT → 2,4-dinitro-benzaldehyde → 2,4-dinitrobenzoic acid →

Keywords： presence 2 4-DNT competition laboratory scavenger

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CO₂ methanation and co-methanation of CO and CO₂ over Mn-promoted Ni/Al₂

Kechao Zhao,Zhenhua Li,Li Bian

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2, Pages 273-280 doi: 10.1007/s11705-016-1563-5

Abstract: A series of Mn-promoted 15 wt-% Ni/Al O catalysts were prepared by an incipient wetness impregnation method. The effect of the Mn content on the activity of the Ni/Al O catalysts for CO methanation and the co-methanation of CO and CO in a fixed-bed reactor was investigated. The catalysts were characterized by N physisorption, hydrogen temperature-programmed reduction and desorption, carbon dioxide temperature-programmed desorption, X-ray diffraction and high-resolution transmission electron microscopy. The presence of Mn increased the number of CO adsorption sites and inhibited Ni particle agglomeration due to improved Ni dispersion and weakened interactions between the nickel species and the support. The Mn-promoted 15 wt-% Ni/Al O catalysts had improved CO methanation activity especially at low temperatures (250 to 400 °C). The Mn content was varied from 0.86% to 2.54% and the best CO conversion was achieved with the 1.71Mn-Ni/Al O catalyst. The co-methanation tests on the 1.71Mn-Ni/Al O catalyst indicated that adding Mn markedly enhanced the CO methanation activity especially at low temperatures but it had little influence on the CO methanation performance. CO methanation was more sensitive to the reaction temperature and the space velocity than the CO methanation in the co-methanation process.

Keywords： Mn promotion nickel catalysts CO₂ methanation co-methanation of CO and CO₂

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Synthesis of copolymers of 3-acryloyloxymethyl-3′-methyloxetane and 3-(2-(2-(2-Methoxyethylenoxy)ethylenoxy

YE Lin, ZHAO Yumei, FENG Zengguo, BAI Ying, WU Feng

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4, Pages 343-348 doi: 10.1007/s11705-007-0062-0

Abstract: The cationic ring-opening copolymerization of AMO with another oxetane-derived monomer, 3-(2-(2-(2-methoxyethylenoxy

Keywords： 4-butanediol 2-methoxyethylenoxy consistent oxetane-derived copolymer

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Title Author Date Type Operation

Epigenetic dysregulation in hepatocellular carcinoma: focus on polycomb group proteins

Sandy Leung-Kuen Au, Irene Oi-Lin Ng, Chun-Ming Wong

Journal Article

Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium

Yan Chen,Wenyan Li,Wen Li,Renjie Chai,Huawei Li

Journal Article

Disabled homolog 2 is required for migration and invasion of prostate cancer cells

Yinyin Xie,Yuanliang Zhang,Lu Jiang,Mengmeng Zhang,Zhiwei Chen,Dan Liu,Qiuhua Huang

Journal Article

Influence of short chain ceramides and lipophilic penetration enhancers on the nano-structure of stratum corneum model membranes studied using neutron diffraction

Annett SCHROETER, Tanja ENGELBRECHT, Reinhard H. H. NEUBERT

Journal Article

Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Journal Article

Effect of TiO 2 loading on the activity of V/TiO 2 -Al 2 O 3 in the catalytic oxidehydrogenation of ethylbenzene

Xiaohong LI, Wenying LI,

Journal Article

Al₂O₃ and CeO₂-promoted MgO sorbents for CO₂ capture at moderate

Huimei Yu, Xiaoxing Wang, Zhu Shu, Mamoru Fujii, Chunshan Song

Journal Article

A Storage-Driven CO₂ EOR for a Net-Zero Emission Target